Amlodipine + enalapril: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Full Generic Medicine Info

Dosage/Direction for Use Contraindications Special Precautions Adverse Reactions Drug Interactions Action CIMS Class ATC Classification

This information is not country-specific. Please refer to the India prescribing information.

Generic Medicine Info

Contraindications

Hypersensitivity to either component. History of angioedema related to previous exposure to ACE inhibitor. Pregnancy.

Special Precautions

Lactation. Renal and hepatic disease, congestive heart failure; concomitant K supplements & potassium-conserving diuretics, hypovolaemic shock, diuretic therapy; periodic blood count monitoring to preclude neutropaenia or agranulocytosis.

Adverse Reactions

Angioneurotic oedema, nausea, headache, cough, dizziness, fatigue, palpitations, chest pain, flushing, rash; increases in BUN, serum K & creatinine levels may occur; neutropaenia.
Potentially Fatal: NA.

Drug Interactions

Indometacin and other NSAIDs may blunt antihypertensive effect. Diuretics enhance antihypertensive effect.

CIMS Class

ACE Inhibitors/Direct Renin Inhibitors / Calcium Antagonists

ATC Classification

C08CA01 - amlodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
C09AA02 - enalapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.

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